B1 KEY
Sulfates, esters, ethers & other chemistry control the activity of enzymes
Prof. Dr. Uwe Bornscheuer, Prof. Dr. Michael Lammers
In this project we investigate the hypothesis that chemical glycan modifications contribute to carbon sequestration by modulating the enzymatic degradation. B1 KEY builds on recent findings that algal glycans are remarkably stable during algal blooms. We will not only study model systems of enzymes and glycans but also continue to discover new enzymes involved in the degradation of algal glycans. The project’s focus on how chemical modifications protect glycans from enzymatic cascades highlights a potential mechanism for their role in long-term carbon storage.
Subproject Team
Publications
The ISME Journal, Volume 20
March 2026
Fructan utilization by members of marine Gammaproteobacteria involves SusC/D-like proteins
Marie-Katherin Zühlke, Alexandra Bahr, Daniel Bartosik, Vipul Solanki, Michelle Teune, Norma Welsch, Frank Unfried, Tristan Barbeyron, Elizabeth Ficko-Blean, Paula Schoppmeier, Laurie Schiller, Nahja Busse, Disha Banerjee, Lionel Cladière, Alexandra Jeudy, Anne Susemihl, Fabian Hartmann, Diane Jouanneau, Murielle Jam, Matthias Höhne, Mihaela Delcea, Greta Reintjes, Uwe T Bornscheuer, Dörte Becher, Jan-Hendrik Hehemann, Mirjam Czjzek, Thomas Schweder
A1 | A3
B1 | B2 | B3
C2 | C3